Preheat your oven to 350°F (175°C) and grease a 9x5-inch loaf pan.
In a bowl, mix flour, baking powder, baking soda, and salt.
In another bowl, cream the butter and sugar until fluffy.
Add eggs one at a time, mixing well after each.
Stir in vanilla extract and orange zest.
Gradually add the dry ingredients to the wet mixture, alternating with orange juice.
Fold in chopped cranberries gently.
Pour the batter into the prepared loaf pan.
Bake for 50-60 minutes, until a toothpick comes out clean.
Allow to cool before slicing.